Mitochondria are cellular organelles that have long been recognized for their essential role in producing ATP, the chemical form of energy required to fuel a diverse range of biochemical reactions within the cell. In the last decade or so, however, additional roles for mitochondria in a myriad of other homeostatic pathways within the cell have been identified (e.g. apoptosis, non-shivering thermogenesis, iron-sulphur cluster biogenesis, cellular copper homeostasis). We are interested in identifying and characterizing the molecular genetic mechanisms that allow mitochondria to make so many varied, and fundamental, contributions to cell biology.
Our research projects